Whoops! Oprah Winfrey, 63, was accidentally given three hands while posing with Reese Witherspoon and Tom Hanks for Vanity Fair's 24th annual 'Hollywood' issue
Another mistake? People took to Twitter to point out that it looks like Reese has three legs in the photo featured on the magazine's cover
A-list: Nicole Kidman, Tom Hanks, Michael B. Jordan, Zendaya, Jessica Chastain Claire Foy, Michael Shannon, Harrison Ford, Gal Gadot, Vanity Fair editor Graydon Carter and Robert De Niro (L-R) all appear on the new cover
In one of the images, Oprah has a hand on her hip, a hand on her lap, and then a third hand wrapped around Reese's waist.
The two appear to be laughing at something Tom Hanks said, and while Oprah's hands are firmly in front of her, four of her fingers are hugging her A Wrinkle in Time co-star's side.
The mistake prompted people to poke fun of the magazine on Twitter, joking that the superstar does indeed have three hands.
'Listen Oprah might have three hands,' Jason Abbruzzese wrote, while Steve Bayorgeon added: 'Everyone knows Oprah has three hands.'
Interesting thought: One person couldn't resist mentioning Oprah's potential run for president
'I do wonder about Reese’s 3 legs?' someone named Nichole wrote. 'Her flesh is not the same color as the inside of her dress.'
'If you're struggling at work today, just remember that you aren't the person who let photos of Reese Witherspoon with three legs AND Oprah with three hands go to print,' Christine Jackson joked.
Meanwhile, someone named Zoe credited Reese's third leg for her success.
'How does Reese Witherspoon get so much done all at once?' she wrote. 'She produces and stars in movies and TV shows, owns a fashion line, and helps organize the Time’s Up movement all at the same time? Well, it’s probably because she has three legs.'
Out and about: Reese was all smiles on Thursday while taking her son Tennessee James Toth to school in Los Angeles
Advocate: Reese supported the 'Time's Up' movement while wearing a black sweater representing the cause
The possible snafu caught so much attention, Reese actually responded to the controversy on Twitter.
'Well...I guess everybody knows now...I have 3 legs,' she wrote. 'I hope you can still accept me for who I am. ( and I will never apologize for snuggling @Oprah .. if you get the opportunity, I highly recommend it.'
The actress was all smiles on Thursday while taking her son Tennessee James Toth to school in Los Angeles.
Reese, a vocal advocate for gender equality, supported the 'Time's Up' movement while wearing a black sweater representing the cause.
She paired the top with cropped, flared jeans and leopard ankle boots for the quick school run.